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We all know about CBD (Cannabidiol) but there's a new kid on the block - CBG. CBG (Cannabigerol) is another compound of the cannabis plant, but it's not just any compound. It's known as the Mother Compound. CBG is found in much less abundance in the plant and this makes it difficult to extract in large quantities. It's holds the DNA of all the other compounds. They all start their life as CBG. As the plant grows, CBG is turned into mainly THC or CBD. Typically, a fully grown plant will have only 1% CBG left after converting to other compounds. Growers are experimenting with crossbreeding of strains to obtain higher levels of CBG.
There is far less research on CBG than on THC or CBD.
As of 2019, no clinical research has been conducted to test the specific effects of cannabigerol in humans.
Cannabigerol is under laboratory research to determine its pharmacological properties and potential effects in disease conditions. Contrary to the major psychoactive cannabinoid THC, cannabigerol antagonizes CB1 receptors and is both an alpha2-adrenoceptor agonist and moderate 5HT1A receptor antagonist. Cannabigerol displays CB1 and CB2 binding affinity, and has been evaluated in laboratory models of colitis.
The human body’s built-in endocannabinoid system (ECS) works to keep the body in its balanced state of homeostasis. While there are specific details about how cannabinoids work, in general the endocannabinoid system performs different functions specific to each area of the body. For example, at an injury site, the ECS can help regulate immune cells to limit inflammation.
CBG has been found to act on very specific physiological systems and problems, and results for medicinal use are promising:
Scientists are excited about these initial CBG results and are promoting future research with CBG alone or CBG in combination with other cannabinoids and therapies for the treatment of multiple maladies. Because it is non-psychotropic, CBG has a promising wide range of potential applications not only for the problems mentioned above, but also as an analgesic, therapy for psoriasis, and as an antidepressant.
We are now stocking the UK's first high strength full spectrum CBG oil that also has equal amounts of CBD too!